Trials / Completed
CompletedNCT00224315
Clozapine-Augmentation With Ziprasidone or Risperidone, a Randomized, Prospective Trial
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 24 (planned)
- Sponsor
- Central Institute of Mental Health, Mannheim · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
We aim to compare the augmentation of clozapine with ziprasidone or risperidone in a randomized, prospective manner.
Detailed description
Partial response of schizophrenic psychoses to a monotherapy with clozapine is a frequent problem of clinical psychiatry. Current problems are treatment resistant positive and/or negative symptoms, as well as side effects. Therefore, different strategies of augmentations have been applied. Based on successful experiences in case reports and results of other work groups, we aim to compare the augmentation of clozapine with ziprasidone or risperidone in a randomized, prospective manner.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | ziprasidone | |
| DRUG | risperidone |
Timeline
- Start date
- 2003-11-01
- Completion
- 2006-09-01
- First posted
- 2005-09-22
- Last updated
- 2008-06-04
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00224315. Inclusion in this directory is not an endorsement.