NCT00222664

Qidong Hepatitis B Intervention Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 80,000 (planned)
• Sponsor: University of Oxford · Academic / Other
• Sex: All
• Age: 0 Years
• Healthy volunteers: —

Summary

During 1983-1990 in the Jiangsu province of China, 80,000 infants were randomised by area of birth between control, standard Hepatitis B vaccination (at 0, 1 and 6 months of age) and standard vaccination plus a booster dose at about 2 to 3 years of age. The aim is to prevent establishment of chronic HBV infection in early childhood, hence to prevent the morbidity of chronic hepatitis B in young adolescents and the incidence/mortality several decades later from liver cancer and other HBV related chronic liver diseases. Long-term follow-up through central registries will determine the impact of vaccination on liver cancer incidence and mortality.

Conditions

• Hepatitis B
• Liver Neoplasms
• Liver Diseases

Interventions

Type	Name	Description
BIOLOGICAL	Hep-V Vax

Timeline

• Start date: 1983-09-01
• Completion: 2004-12-01
• First posted: 2005-09-22
• Last updated: 2005-09-22

Locations

3 sites across 2 countries: China, United Kingdom