NCT00222638

Influenza Vaccination and Oral Anticoagulant Therapy

Randomized Blinded Cross-Over Clinical Trial Investigate the Interactions Between Influenza Vaccination and Oral Anticoagulant Therapy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (planned)
• Sponsor: University Of Perugia · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate INR and INR related index and Warfarin weekly dosage variations after Influenza Vaccination

Detailed description

The pharmacokinetic and the pharmacodynamic interactions and the possible clinical events connected with the simultaneous administration of Oral Anticoagulants (OA) and the influenza virus vaccine were evaluated in several small studies which yielded conflicting results, thus encouraging additional investigations with prospective studies in order to obtain a more consistent evidence about the safety and efficacy of vaccination against influenza virus in patients on OA Treatment.

Conditions

• Anticoagulants
• Influenza Vaccines

Interventions

Type	Name	Description
DRUG	Influenza vaccination

Timeline

• Start date: 2004-10-01
• Completion: 2005-05-01
• First posted: 2005-09-22
• Last updated: 2005-09-22

Locations

1 site across 1 country: Italy