NCT00219908

Evaluation of a New Therapeutic Strategy in Early and Active Relapsing-Remitting Multiple Sclerosis

Evaluation of a New Therapeutic Strategy in Early and Active Relapsing-Remitting Multiple Sclerosis: Induction Treatment With Mitoxantrone Followed by Long-Term Treatment With Interferon-beta1b

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 124 (planned)
• Sponsor: Rennes University Hospital · Academic / Other
• Sex: —
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to determine whether a therapeutic strategy combining mitoxantrone and interferon beta1b can delay disease progression of at least one point on EDSS scale in patients with clinically very active relapsing-remitting multiple sclerosis.

Conditions

• Relapsing-Remitting Multiple Sclerosis

Interventions

Type	Name	Description
DRUG	Mitoxantrone

Timeline

• Start date: 1999-07-01
• Completion: 2006-06-01
• First posted: 2005-09-22
• Last updated: 2005-12-22

Locations

23 sites across 2 countries: France, Italy