Clinical Trials Directory

Trials / Completed

CompletedNCT00215696

A Study to Treat Patients Whose Chronic Angina Symptoms Are Not Relieved by Medication and Have an Area of the Heart That Cannot be Treated by Standard Therapies

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy of BIOBYPASS® (ADGVVEGF121.10NH) Delivered by NOGA™-GUIDED/MYOSTAR™ Catheter in "No Option" Patients With Class II-IV Stable Angina

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
129 (planned)
Sponsor
GenVec · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of this study is to determine whether treatment with an experimental gene therapy (BIOBYPASS®) will reduce angina in study participants by stimulating the growth of new blood vessels. This will be measured by testing whether participants are able to exercise longer without experiencing angina after treatment, as compared to before treatment. Additionally, this study will collect information about any side effects that might be related to the treatment with the experimental therapy.

Conditions

Interventions

TypeNameDescription
GENETICBioBypass®

Timeline

Start date
2005-04-01
First posted
2005-09-22
Last updated
2011-05-13

Locations

3 sites across 2 countries: Denmark, Israel

Source: ClinicalTrials.gov record NCT00215696. Inclusion in this directory is not an endorsement.