NCT00213629

myoARRAY and TcLandscape Analysis for the Diagnosis of Inflammatory Myopathies

Transcriptome Analysis Through a Dedicated Macro-array and TcLandscape Repertoire Analysis for Diagnosis of Myositis.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: University Hospital, Rouen · Academic / Other
• Sex: All
• Age: 18 Years – 76 Years
• Healthy volunteers: Not accepted

Summary

The diagnosis of the different forms of inflammatory myopathies (polymyositis, dermatomyositis, inclusion-body myositis...) remains difficult which may lead to unappropriate patient care. Objective 1 : to develop and evaluate the diagnostic value of a dedicated DNA-array (myoARRAY) for adult-onset muscular diseases with focus on inflammatory myopathies. Objective 2 : to evaluate the diagnostic value of T cell repertoire (TcLand) analysis to distinguish different forms of inflammatory myopathies.

Conditions

• Polymyositis
• Dermatomyositis

Interventions

Type	Name	Description
OTHER	transcriptome analysis	transcriptome analysis from muscle biopsy
OTHER	T cell repertoire analysis	blood T cell repertoire analysis

Timeline

• Start date: 2004-11-01
• Primary completion: 2010-07-01
• Completion: 2010-07-01
• First posted: 2005-09-21
• Last updated: 2012-02-16

Locations

1 site across 1 country: France