NCT00213304

The Safety of Oka Varicella in Children Prior to Solid Organ Transplantation

Safety and Immunogenicity of Live Attenuated Oka/Merck Varicella Vaccine in Children Listed to Undergo Solid Organ Transplantation

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 21 (actual)
• Sponsor: The Hospital for Sick Children · Academic / Other
• Sex: All
• Age: 9 Months – 18 Years
• Healthy volunteers: Not accepted

Summary

This study sought to determine the safety of the varicella vaccine pre- and post-transplantation when given to pediatric patients listed for solid organ transplantation. The study assessed the antibody response to a two-dose vaccine regimen and determined the durability of that antibody response at several intervals in the post-transplant period. As a secondary objective, the relationship between antibody titers and different variables were explored

Conditions

• Organ Transplantation
• Immunosuppression

Interventions

Type	Name	Description
BIOLOGICAL	varicella vaccine (VARIVAX)

Timeline

• Start date: 1999-06-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2005-09-21
• Last updated: 2021-08-24

Locations

1 site across 1 country: Canada