NCT00212485

Study to Evaluate the Use of Ultrasound in the Diagnosis of Hemophilic Joint Disease

Evaluation of the Role of Power Doppler Sonography in the Diagnosis of Hemophilic Joint Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: New York Presbyterian Hospital · Academic / Other
• Sex: All
• Age: 1 Year – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to see whether power Doppler sonography (PDS) can be used to diagnose synovitis in patients with inherited bleeding disorders.

Detailed description

Aim #1 - To determine if PDS can be used to diagnose synovial hypertrophy and inflammation in joint disease associated with inherited bleeding disorders. MRI will be used as a reference standard. Aim #2 - To determine if PDS can be used to assess therapeutic response to treatment. Aim #3 - To determine if PDS can be used as a screening tool for diagnosing early synovitis.

Conditions

• Inherited Bleeding Disorders

Interventions

Type	Name	Description
PROCEDURE	Power Doppler Sonography	Power Doppler with gray-scale sonography is used to detect and quantify alterations in vascularity inside knee, elbow and ankle joints.
PROCEDURE	MRI	Magnetic Resonance Imaging with intravenous gadolinium contrast will be done using a standardized protocol, including a spin echo T2 weighted image and gradient echo images.

Timeline

• Start date: 2005-09-01
• Primary completion: 2008-04-01
• Completion: 2009-05-01
• First posted: 2005-09-21
• Last updated: 2010-07-01

Locations

1 site across 1 country: United States