NCT00212381

Oral Diindolylmethane (DIM) for the Treatment of Cervical Dysplasia

Diindolylmethane (DIM) Dietary Supplementation: A Nonsurgical Treatment for Cervical Intraepithelial Neoplasia (CIN)

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 62 (estimated)
• Sponsor: New York Presbyterian Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

To determine if the use of oral Diindolylmethante (DIM), a marketed cruciferous vegetable based dietary supplement (Bioresponse-DIM), is associated with the regression of cervical dysplasia in otherwise healthy women.

Detailed description

To determine if the use of oral Diindolylmethane (DIM), a marketed cruciferous vegetable based dietary supplement (BioResponse-DIM®), is associated with the regression of cervical dysplasia in otherwise healthy women. Additionally, the study aims to see how the use of the BioResponse-DIM supplement correlates with cervical HPV colonization, and to asses the tolerability of daily DIM supplementation

Conditions

• Cervical Dysplasia

Interventions

Type	Name	Description
DRUG	di indolylmethane (DIM)	This is the agent being studies. Similar agents have been reported to have potential activity.
DIETARY_SUPPLEMENT	Red rice bran	this will act as the active comparator. The sponsor provided this as the "placebo" arm since it is a filler component of their DIM capsules

Timeline

• Start date: 2000-09-01
• Primary completion: 2006-01-01
• Completion: 2010-07-01
• First posted: 2005-09-21
• Last updated: 2017-03-29

Locations

1 site across 1 country: United States