NCT00210314

Phase II Trial of Combined Modality Treatment in Primary Central Nervous System Lymphoma

Randomized Phase II Trial on Primary Chemotherapy With High-dose Methotrexate, Alone or Associated With High-dose Cytarabine, Followed by Response- and Age-tailored Radiotherapy for Immunocompetent Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 79 (actual)
• Sponsor: International Extranodal Lymphoma Study Group (IELSG) · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Aim of the study is to establish in a prospective, randomized clinical trial the activity of primary chemotherapy containing high dose-methotrexate, alone or combined with high dose cytarabine, in patients with primary central nervous system lymphoma

Conditions

• Lymphoma, B Cell

Interventions

Type	Name	Description
DRUG	high dose methotrexate
DRUG	high dose cytarabine
RADIATION	radiotherapy

Timeline

• Start date: 2003-07-01
• Primary completion: 2007-09-01
• Completion: 2007-12-01
• First posted: 2005-09-21
• Last updated: 2015-03-30

Locations

1 site across 1 country: Switzerland