NCT00210210

Administration of Ketamine to Prevent the Post-operative Pain

Effect of Ketamine, at the Induction and Its Maintenance to Prevent the Post-operative Pain: Clinical Trial in Cancerology

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 230 (actual)
• Sponsor: Institut Bergonié · Academic / Other
• Sex: Female
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The surgery of breast cancer is responsible for post-operative pain, needing in about 30% some morphine consumption; like that, the association of ketamine with general anaesthesia may decrease morphine's use and so its adverse effects. The purpose is to evaluate the analgesic effect of a receptor NMDA's antagonist ( ketamine)

Conditions

• Postoperative Pain
• Breast Cancer

Interventions

Type	Name	Description
DRUG	Ketamine
DRUG	Saline solution

Timeline

• Start date: 2004-01-31
• Primary completion: 2005-07-31
• Completion: 2005-12-31
• First posted: 2005-09-21
• Last updated: 2025-09-19
• Results posted: 2025-09-08

Locations

1 site across 1 country: France