NCT00209365

The Role of Pollen Starch Granules in Pollen Challenge Studies in the Fraunhofer Environmental Exposure Unit

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (planned)
• Sponsor: Fraunhofer-Institute of Toxicology and Experimental Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to explore the contribution of pollen starch granules to the induced symptoms and airway inflammation in patients with allergic rhinitis and mild asthma in a controlled pollen exposure(pollen challenge room at the Fraunhofer ITEM). Starch granules are released from the pollen grains and are considered to be the allergen carriers of the pollen. The hypothesis is proposed that pollen starch granules are important in the induction of airway inflammation and airway hyperresponsiveness.

Conditions

• Asthma
• Seasonal Allergic Rhinitis

Interventions

Type	Name	Description
PROCEDURE	exposure to grass pollen/starch granules

Timeline

• Start date: 2005-09-01
• Completion: 2005-12-01
• First posted: 2005-09-21
• Last updated: 2017-02-15

Locations

1 site across 1 country: Germany