NCT00203112

Safety and Efficacy Study of Copaxone Administered in Combination With Minocycline

A Multi-Centered, Randomized, Double-Blind, Placebo-Controlled, Parallel Study Assessing the Add-on Effect of Minocycline in Relapsing-Remitting Multiple Sclerosis (RR-MS) Subjects Treated With Glatiramer Acetate (GA).

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 44 (actual)
• Sponsor: Teva Branded Pharmaceutical Products R&D, Inc. · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

This study investigates the add-on effect of oral minocycline in subjects treated with daily injection of Copaxone. Copaxone and minocycline are thought to have differential modes of actions that may complement each other in treating MS symptoms.

Conditions

• Relapse Remitting Multiple Sclerosis

Interventions

Type	Name	Description
DRUG	glatiramer acetate with minocycline	Subcutaneous injection glatiramer acetate 20mg, with oral minocycline 100mg
DRUG	Glatiramer acetate with placebo	Subcutaneous injection glatiramer acetate 20mg, with oral placebo

Timeline

• Start date: 2004-06-01
• Primary completion: 2006-06-01
• Completion: 2006-07-01
• First posted: 2005-09-20
• Last updated: 2011-04-12