NCT00200616

Usefulness of Antimicrobial Prophylaxis in Children With Isolated Vesico-Ureteral Reflux.

Antimicrobial Prophylaxis in Children With Isolated Vesico-Ureteral Reflux. A Randomised Prospective Study of Continuous Low Dose of Trimethoprim-Sulfamethoxazole Versus Surveillance.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 232 (planned)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 1 Day – 3 Years
• Healthy volunteers: Not accepted

Summary

Randomized, prospective, multicenter study in order to assess the usefulness of antimicrobial prophylaxis in children with isolated vesico-ureteral reflux (grade III or less).

Detailed description

A voiding cystourethrogram was performed for each child less than 3 years old with a first urinary tract infection. In case of vesico-ureteral reflux, a randomization was done between continuous antimicrobial prophylaxis with low dose of trimethoprim-sulfamethoxazole and no antibioprophylaxis. Duration of follow up was 18 months.

Conditions

• Urinary Tract Infection

Interventions

Type	Name	Description
PROCEDURE	Antimicrobial prophylaxis

Timeline

• Start date: 2001-04-01
• Primary completion: 2006-07-01
• Completion: 2006-07-01
• First posted: 2005-09-20
• Last updated: 2008-07-01

Locations

1 site across 1 country: France