NCT00200226

Oral Misoprostol Before Endometrial Biopsy

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: Memorial University of Newfoundland · Academic / Other
• Sex: Female
• Age: 19 Years
• Healthy volunteers: Accepted

Summary

An endometrial biopsy involves a thin tube being passed through the cervix (opening of the uterus) to obtain a sample of the lining of the uterus. Sometimes there may be discomfort with this procedure especially if the cervix is not dilated or opened. Previous research has suggested that taking a drug called misoprostol may help the cervix to start to dilate or open. This study will see if misoprostol will help open the cervix for an endometrial biopsy, to lessen the discomfort and make the biopsy easier to perform.

Conditions

• Endometrial Biopsy

Interventions

Type	Name	Description
DRUG	misoprostol	misoprostol 400mcg 12 hrs prior to procedure
DRUG	vitamin B6	Vitamin B6 50 mg orally 12 hrs prior to procedure

Timeline

• Start date: 2003-02-01
• Completion: 2007-09-01
• First posted: 2005-09-20
• Last updated: 2007-09-21

Locations

2 sites across 1 country: Canada