NCT00199498

Right Apical Versus Septal Pacing Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (estimated)
• Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to examine whether RV (right ventricular)septal pacing has any effect on LV ( left ventricular) function than RV apical pacing in patients who require ventricular pacing.

Detailed description

The primary objective of this study is to compare the effect of RV pacing site on LV systolic function as measured by LVEF (left ventricular ejection fraction). Secondary objectives of this trial include: 1. to compare the effect of RVSeptal(RVS) versus RVApical(RVA)pacing on other indices of systolic and diastolic LV function 2. to compare the rate of heart failure-related hospitalization between RVS versus RVA pacing 3. to compare new-onset atrial fibrillation and stroke rates between RVS versus RVA pacing 4. to assess the effect of RVA versus RVS pacing on quality of life and functional capacity 5. to compare the rate of successful pacemaker lead implantation, complications and chronic electrical performance of RVS versus RVA pacing

Conditions

• Heart Block
• Heart Failure

Interventions

Type	Name	Description
DEVICE	Apical RV lead placement	RV lead implanted ( according to randomization )at the apex
DEVICE	Septal RV lead placement	RV lead is implanted (according to randomization), on septum

Timeline

• Start date: 2005-04-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2005-09-20
• Last updated: 2016-04-13

Locations

1 site across 1 country: Canada