Trials / Unknown
UnknownNCT00199121
A Pilot Study of Triple NtRTI/NsRTI Therapy in Antiretroviral Naive HIV-1 Infected Patients
An Open, Single-Arm, Multi-Center, Phase IV Pilot Study of Treatment of Antiretroviral Naive HIV-1 Infected Patients With Tenofovir Disoproxil Fumarate in Combination With Emtricitabine and Zidovudine
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Johann Wolfgang Goethe University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate the antiviral effect and durability of antiviral response (HIV-1 RNA PCR) and safety of a triple NtRTI/NsRTI therapy in antiretroviral naive patients. Patients will receive TDF plus FTC plus AZT for at least 48 weeks. Further objectives are to evaluate resistance pathways in failing patients treated with TDF/FTC/AZT and to evaluate a treatment strategy of sparing PIs and NNRTIs for later treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Zidovudine (drug) |
Timeline
- First posted
- 2005-09-20
- Last updated
- 2005-12-14
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00199121. Inclusion in this directory is not an endorsement.