Trials / Completed
CompletedNCT00199017
German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults
Multicenter Trial for Treatment Optimization in T-lymphoblastic Lymphoma in Adults and Adolescents Older Than 15 Years (GMALL T-LBL 1/2004) (Amend 1)
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 75 (estimated)
- Sponsor
- Johann Wolfgang Goethe University Hospital · Academic / Other
- Sex
- All
- Age
- 15 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
This study evaluates the efficacy and tolerability of treatment for T-lymphoblastic lymphoma (T-LBL) according to a protocol for acute lymphoblastic leukemia. Patients receive one year of intensive cyclical chemotherapy with additional prophylaxis for central nervous system (CNS) relapse by intrathecal therapy and cranial irradiation and mediastinal irradiation after induction chemotherapy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Dexamethasone/Prednisolone | |
| DRUG | Cyclophosphamide | |
| DRUG | Vincristine | |
| DRUG | Daunorubicin | |
| DRUG | Asparaginase | |
| DRUG | G-CSF | |
| DRUG | Mercaptopurine | |
| DRUG | Cytarabine | |
| DRUG | Methotrexate | |
| DRUG | VP16 | |
| DRUG | Vindesine | |
| DRUG | Adriamycin | |
| DRUG | Thioguanine | |
| DRUG | HDARAC | |
| PROCEDURE | CNS irradiation | |
| PROCEDURE | Mediastinal irradiation | |
| DRUG | Cladribine |
Timeline
- Start date
- 2004-04-01
- Primary completion
- 2009-03-01
- First posted
- 2005-09-20
- Last updated
- 2010-08-23
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00199017. Inclusion in this directory is not an endorsement.