Clinical Trials Directory

Trials / Terminated

TerminatedNCT00197145

Study Of Chemokine Coreceptor 5 (CCR5) Antagonist GW873140 In R5-Tropic Treatment-Experienced HIV-Infected Subjects

A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel Group Study to Compare the Efficacy and Safety of GW873140 400mg BID in Combination With a Ritonavir-containing Optimized Background Therapy (OBT) Regimen Versus Placebo Plus OBT Over 48 Weeks.

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
24 (actual)
Sponsor
ViiV Healthcare · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the safety and efficacy of the CCR5 antagonist GW873140 or placebo in combination with an optimized background regimen in treatment-experienced HIV-infected subjects with R5-tropic virus

Conditions

Interventions

TypeNameDescription
DRUGGW873140400 mg twice daily

Timeline

Start date
2005-07-21
Primary completion
2007-09-11
Completion
2007-09-11
First posted
2005-09-20
Last updated
2018-11-02
Results posted
2018-11-02

Locations

55 sites across 3 countries: United States, Canada, Puerto Rico

Source: ClinicalTrials.gov record NCT00197145. Inclusion in this directory is not an endorsement.