Clinical Trials Directory

Trials / Completed

CompletedNCT00197015

Immunogenicity & Safety of Hepatitis A Vaccine Co-admin With a Measles/Mumps/Rubella & a Varicella Vaccine in Children

Immunogenicity & Safety of GSK Biologicals' Inactivated Hepatitis A Vaccine (Havrix™) Co-administered With Merck & Company, Inc. Measles-Mumps-Rubella Vaccine (M-M-RII) & Merck & Co Varicella Vaccine (VARIVAX™) to Children 15 Months of Age

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
1,474 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
12 Months – 13 Months
Healthy volunteers
Accepted

Summary

This is a study to evaluate the immune response and safety of GSK Biologicals 2-dose inactivated hepatitis A vaccine when administered with a measles/mumps/rubella vaccine and a varicella (chickenpox) vaccine in children as young as 15 months of age. The Protocol Posting has been updated in order to comply with the FDA Amendment Act, Sep 2007.

Detailed description

An open, controlled comparison of Havrix™ administered alone or with MMR II and Varivax™. The three groups evaluated are: 1) Havrix™ alone, 2) Havrix™ + MMR II and Varivax™ and 3) MMR II and Varivax™ followed by Havrix™ one month later.

Conditions

Interventions

TypeNameDescription
BIOLOGICALHavrix®2 doses administered intramuscularly
BIOLOGICALM-M-R®II1 dose administered subcutaneously
BIOLOGICALVARIVAX®1 dose administered subcutaneously

Timeline

Start date
2003-10-06
Primary completion
2009-06-09
Completion
2009-06-09
First posted
2005-09-20
Last updated
2018-07-31
Results posted
2010-04-01

Locations

42 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00197015. Inclusion in this directory is not an endorsement.