NCT00196222

European Multicenter Study Radiofrequency (RF) Versus Cryo in Atrioventricular Nodal Reentry Tachycardia (AVNRT)

European Multicenter Study RF Versus Cryo in AVNRT: A Randomized Study Comparing Cryo-Energy vs. Radiofrequency-Energy Ablation Technique for AV Nodal Reentry Tachycardia (AVNRT)

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 509 (actual)
• Sponsor: Deutsches Herzzentrum Muenchen · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

In this randomized study, two energy sources for the ablation of AV nodal reentry tachycardia are compared: The standard technique of radiofrequency energy delivery is compared with the new approach of cryo-energy application.

Detailed description

The ablation of AV nodal reentry tachycardia with radiofrequency (RF) energy delivering catheters is a standard procedure and in experienced EP laboratories, the safety and efficacy of this approach is very high. However, the potential complication of higher degree AV conduction block, requiring in some instances implantation of a pacemaker, is a major drawback of this approach. We want to compare in this randomized study the safety and efficacy of standard RF ablation with the cryo-ablation technique. This relatively new technique is thought to offer more safety concerning higher degree AV conduction block.

Conditions

• Atrioventricular Nodal Reentry Tachycardia

Interventions

Type	Name	Description
PROCEDURE	RF-ablation	RF ablation/modulation of the slow pathway in AV nodal reentrant tachycardia
PROCEDURE	cryo ablation	Cryo ablation/modulation of the slow pathway in AV nodal reentrant tachycardia

Timeline

• Start date: 2003-03-01
• Primary completion: 2008-11-01
• Completion: 2009-05-01
• First posted: 2005-09-20
• Last updated: 2013-07-04

Locations

10 sites across 1 country: Germany