Trials / Terminated
TerminatedNCT00188045
Hemodynamic Effects of Chronic Administration of Spironolactone and/or Propranolol in Alcoholic Cirrhotic Patients
Hemodynamic Effects of Chronic Administration of Spironolactone, Propranolol and Their Association in Alcoholic Cirrhotic Patients
- Status
- Terminated
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 54 (planned)
- Sponsor
- University Hospital, Angers · Other Government
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study was assesment of splanchnic and systemic hemodynamic effects of chronic administration (2 month) of spironolactone or propranolol, alone or in association in alcoholic cirrhotic patients. The patients were randomized in 4 groups (aldactone 150 mg/day, propranolol 160 mg/day, aldactone 150 mg/day + propranolol 160 mg/day, placebo). Systemic and splanchnic hemodynamic effect were evaluated by hepatic venous pressure gradient measurements before and after 2 month of treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Propranolol - Spironolactone |
Timeline
- Start date
- 1995-04-01
- Completion
- 2003-12-01
- First posted
- 2005-09-16
- Last updated
- 2017-11-01
Source: ClinicalTrials.gov record NCT00188045. Inclusion in this directory is not an endorsement.