NCT00186758

Transcranial Magnetic Stimulation in Bipolar Depression

A Randomized, Sham Controlled, Crossover Trial of rTMS for Bipolar Depression

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: St. Joseph's Healthcare Hamilton · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

To compare antidepressant efficacy of left or right to sham Repetitive Transcranial Magnetic Stimulation (rTMS) to determine if non-responders can become responders if treated on the other side of the hemisphere (rTMS)

Detailed description

Patients will be assigned to one of 3 treatment arms for 10 days of treatment with either left high frequency or right high frequency, or sham rTMS. After 10 days of treatment, and no improvement, another 10 days of treatment follows, this time with the coil placed on the other hemisphere. Subjects will be followed for 2 months respectively with unrestricted treatment provided by their regular physician. Mood stabilizers will be continued throughout this trial.

Conditions

• Bipolar Affective Disorder

Interventions

Type	Name	Description
DEVICE	Transcranial Magnetic Stimulation (TMS)	Phase l clients receive either True or Sham TMS treatments on left or right side of head for 10 days. Phase ll clients will receive either Sham or True TMS treatments on the other side of the head - the same type as in phase l -

Timeline

• Start date: 2002-07-01
• Primary completion: 2011-07-01
• Completion: 2011-07-01
• First posted: 2005-09-16
• Last updated: 2011-08-03

Locations

1 site across 1 country: Canada