Trials / Completed
CompletedNCT00186563
A Human In-vivo Model for the Detection of Inflammatory and Nociceptive Biomarkers
Proof-of-concept Study for Bio-marker Assay Validation in Humans
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 13 (planned)
- Sponsor
- Martin Angst · Academic / Other
- Sex
- All
- Age
- 21 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
This study aims to establish a novel approach assisting the rational development of analgesic and anti-inflammatory drugs. In a first step we will test in healthy human volunteers whether proteins mediating inflammation and pain can be detected in an experimentally induced inflammatory skin lesion. Fluids that will be used to detect such proteins will be collected from the inflamed skin site via small porous catheters. We wish to establish the expression pattern of different proteins and correlate it with various tests assessing pain.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Micro-plasmapheresis |
Timeline
- First posted
- 2005-09-16
- Last updated
- 2013-06-19
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00186563. Inclusion in this directory is not an endorsement.