NCT00186290

Allo BMT in Advanced Leukemia or High Grade Lymphoma

Fractionated Total Body Irradiation (FTBI), Etoposide (VP-16) and Cyclophosphamide (CY) Followed by Allogeneic Bone Marrow Transplantation for Patients With Advanced Leukemia or High Grade Lymphoma

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 145 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the role of ablative allogeneic hematopoietic cell transplantation in the treatment of advanced leukemia or lymphoma.

Detailed description

To determine the disease free survival and overall survival of patients with ALL and ANLL after induction failure, in relapse, or subsequent remission from CML in several phases or recurrent lymphoblastic lymphoma who receive fractionated TBI, etoposide and cyclophosphamide followed by allogenic bone marrow grafting from histocompatible sibling donors. Fractionated Total Body Irradiation (FTBI), Etoposide (VP-16) and Cyclophosphamide (CY) Followed by Allogeneic Bone Marrow Transplantation for Patients with Advanced Leukemia or High Grade Lymphoma

Conditions

• Lymphoma, Non-Hodgkin
• Leukemia
• Blood and Marrow Transplant (BMT)
• Lymphomas: Non-Hodgkin

Interventions

Type	Name	Description
PROCEDURE	ablative allogeneic hematopoietic cell transplantation

Timeline

• Start date: 1989-12-01
• Primary completion: 2009-10-01
• Completion: 2009-10-01
• First posted: 2005-09-16
• Last updated: 2010-10-11

Locations

1 site across 1 country: United States