NCT00186069

Magnesium Sulfate vs Placebo for Placental Abruption

Randomized, Double Blind Trial of Magnesium Sulfate Tocolysis Versus Intravenous Saline for Suspected Placental Abruption

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the safety and efficacy of magnesium sulfate for preterm suspected abruption.

Detailed description

We hope to learn if there is a difference in the efficacy of intravenous magnesium sulfate versus intravenous saline infusion in the resolution of vaginal bleeding and contractions in patients with a suspected placental abruption.

Conditions

• Abruptio Placentae

Interventions

Type	Name	Description
DRUG	Magnesium Sulfate	Magnesium Sulfate 4 gram bolus, followed by a maintenance dose at 2 grams per hour. Rate increases up to 4 grams per hour may be administered per physician discretion.
OTHER	Normal Saline	Normal Saline infusion of 4 gram bolus, followed by 2 grams per hour with rate increases up to 4 grams per hour per physician discretion.

Timeline

• Start date: 2004-03-01
• Primary completion: 2014-06-01
• Completion: 2017-11-01
• First posted: 2005-09-16
• Last updated: 2018-01-02
• Results posted: 2017-04-20

Locations

2 sites across 1 country: United States