Clinical Trials Directory

Trials / Completed

CompletedNCT00185861

Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant Glioma

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
12 (actual)
Sponsor
Stanford University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

To investigate the safety of delivering arsenic trioxide (ATO) in combination with stereotactic radiotherapy in recurrent malignant glioma by performing an open label, Phase I dose escalation trial. Results from this study will provide a basis for further study of ATO combined with radiation therapy as a radiosensitizer for malignant brain tumors in future Phase II studies.

Conditions

Interventions

TypeNameDescription
DRUGArsenic Trioxide
PROCEDUREStereotactic radiosurgery

Timeline

Start date
2003-12-01
Primary completion
2008-01-01
Completion
2009-04-01
First posted
2005-09-16
Last updated
2009-04-09

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00185861. Inclusion in this directory is not an endorsement.