Clinical Trials Directory

Trials / Unknown

UnknownNCT00185263

Safety and Efficacy of Intracoronary Ad5FGF-4 in Patients With Stable Angina

A Multinational Multicenter, Randomized , Double Blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Ad5FGF-4 in Patients With Stable Angina

Status
Unknown
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
116 (actual)
Sponsor
Cardium Therapeutics · Industry
Sex
All
Age
30 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine whether a single intracoronary infusion of Ad5FGF-4 is effective in improving exercise capacity measured by exercise treadmill testing, angina functional class, patient symptoms, quality of life, and cardiovascular outcomes. To doses are to be studied, 2.87x10(8) and 2.87x10(9) viral particles, to evaluate the dose-response of Ad5FGF-4. Short-term and long-term safety of Ad5FGF-4 will also be evaluated.

Conditions

Interventions

TypeNameDescription
GENETICAdF5FGF-4 vs. PlaceboIntracoronary infusion

Timeline

Start date
2002-03-01
Primary completion
2005-01-01
Completion
2008-11-01
First posted
2005-09-16
Last updated
2008-11-06

Source: ClinicalTrials.gov record NCT00185263. Inclusion in this directory is not an endorsement.

Safety and Efficacy of Intracoronary Ad5FGF-4 in Patients With Stable Angina (NCT00185263) · Clinical Trials Directory