NCT00184834

Quality of Life and Liver Metastases

Quality of Life After Surgical Treatment of Colorectal Liver Metastases

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (planned)
• Sponsor: Radboud University Medical Center · Academic / Other
• Sex: All
• Age: 0 Years
• Healthy volunteers: Not accepted

Summary

An increasing aggressiveness in the surgical approach of colorectal liver metastases is observed. This seems only justified when, besides prolongation of survival, also the health status of patients is considered. The aim of this prospective study is to investigate the impact of surgery on health-related quality of life in this specific patient population operated for colorectal liver metastases.Furthermore, as the indications for hepatic resection are broadened and patients with more extensive liver disease are operated on, the chance of non operable disease at laparotomy will increase. The effects of such an event on HRQol are also studied.

Detailed description

In a prospective study several patients groups were identified. Patients undergoing liver resection and/or local ablative therapy. Patients with non operable disease at (explorative) laparotomy and outpatients with non operable disease as shown during work up for liver resection. Several validated instruments on HRQoL were ompleted preoperatively (baseline), a half month after operation and then every three months.

Conditions

• Colorectal Liver Metastases
• Quality of Life

Interventions

Type	Name	Description
BEHAVIORAL	quality of life

Timeline

• Start date: 1999-06-01
• Completion: 2002-11-01
• First posted: 2005-09-16
• Last updated: 2005-09-16

Locations

1 site across 1 country: Netherlands