NCT00184093

Study of Gemcitabine and Concurrent Radiation Followed by Adjuvant Hysterectomy in Bulky Stage Ib and IIa Cervical Carcinoma

Phase I/II Study of Gemcitabine and Concurrent Radiation Followed by Adjuvant Hysterectomy in Bulky Stage Ib and IIa Cervical Carcinoma: Analysis of Prognostic Factors and Determinants of Response: A Pilot Study

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: University of Southern California · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is first to establish what is the ideal dose of gemcitabine, a chemotherapy agent, when given in combination with radiation. In addition, the investigators want to determine the side effects and the effectiveness of this combination. The investigators will also study several markers to try to identify markers or tests that will predict which patients will benefit more from this treatment.

Conditions

• Uterine Cervical Cancer

Interventions

Type	Name	Description
DRUG	Gemcitabine	Gemcitabine weekly x 6 wks with concurrent external radiation

Timeline

• Start date: 1999-06-01
• Primary completion: 2008-05-01
• Completion: 2009-05-01
• First posted: 2005-09-16
• Last updated: 2017-08-15
• Results posted: 2017-08-15

Locations

1 site across 1 country: United States