NCT00181363

Prone Breast Irradiation for Pendulous Breasts

Mamma Board Project: Prone Breast Irradiation for Pendulous Breasts

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Maastricht Radiation Oncology · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

We hypothesize that for large pendulous breasts, breast irradiation in supine and prone position are equivalent with regard to coverage of the PTV, but with a better dose homogeneity in prone position and a smaller radiation exposure of lung and heart.The purpose of this study is to compare the 3-D dose distribution in PTV(Planning Target Volume) and normal tissues in prone position versus supine position.

Detailed description

Local excision followed by adjuvant radiotherapy has become standard treatment for women with early-stage breast cancer. Adjuvant radiotherapy may encounter technical difficulties in patients with pendulous breasts when treated in supine position. Based upon literature and our own preliminary experiences, we hypothesize that for large pendulous breasts, breast irradiation in supine and prone position are equivalent with regard to coverage of the PTV, but with a better dose homogeneity in prone position and a smaller radiation exposure of lung and heart. However, no quantitative data are yet available to test this hypothesis. Therefore, the aim of our study is to compare the 3-D dose distribution in PTV and normal tissues in prone position versus supine position. For treatment in prone-position an in-house developed device, the "mammaboard" was used.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
DEVICE	Mamma board	use of mamma board during radiotherapy

Timeline

• Start date: 2003-12-01
• Primary completion: 2006-07-01
• Completion: 2007-01-01
• First posted: 2005-09-16
• Last updated: 2020-01-28
• Results posted: 2020-01-28

Locations

1 site across 1 country: Netherlands