NCT00180466

PROSPECT: An Imaging Study in Patients With Unstable Atherosclerotic Lesions

Providing Regional Observations to Study Predictors of Events in the Coronary Tree (PROSPECT) An Imaging Study in Patients With Unstable Atherosclerotic Lesions

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 697 (actual)
• Sponsor: Abbott Medical Devices · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

PROSPECT is a multi-center prospective registry of Acute Coronary Syndromes (ACS) patients with single or double vessel coronary artery disease. Approximately 700 patients with ACS will be enrolled into the study at sites in the United States and European Union.

Detailed description

To identify in patients presenting with ACS imaging modalities and/or serologic markers of inflammation which may aid in the identification of non-flow obstructing lesions with an increased risk for future acute coronary events. This study will ascertain the prevalence and clinical significance of non-flow obstructing lesions, which subsequently result in acute coronary events - defined as vulnerable plaque. The safety of regional imaging of non-culprit lesions in ACS patients will also be assessed.

Conditions

• Coronary Disease
• Coronary Artery Disease
• Coronary Restenosis

Timeline

• Start date: 2004-10-01
• Primary completion: 2009-06-01
• Completion: 2009-07-01
• First posted: 2005-09-16
• Last updated: 2010-05-25

Locations

40 sites across 12 countries: United States, Belgium, Denmark, France, Germany, Italy, Netherlands, Poland, Spain, Sweden, Switzerland, United Kingdom