NCT00179868

C-Reactive Protein as a Predictor of Stem Cell Transplant Complications

C-Reactive Protein As a Predictor of Major Transplant Complications in Pediatric Stem Cell Transplant Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 70 (actual)
• Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago · Academic / Other
• Sex: All
• Age: 6 Months – 20 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine if C-Reactive Protein levels are predictive for complications post transplant.

Conditions

• Cancer
• Leukemia
• Stem Cell Transplantation

Interventions

Type	Name	Description
BEHAVIORAL	C-Reactive Protein levels	Each patient enrolled in the study will have a serum quantitative c-reactive protein (crp) level drawn on the day of transplant, day 7 of transplant, and twice weekly after that until recovery of neutrophil count (approximately 20-25 days). Patients will be followed for 100 days post-transplant for the development of the following complications: 1. Sepsis- defined as fever, positive blood culture, need for fluid resuscitation and/or pressor support. 2. Acute GVHD \> grade II defined according to the Seattle criteria 3. VOD- defined according to the modified Seattle criteria

Timeline

• Start date: 2003-01-01
• Primary completion: 2008-02-01
• Completion: 2008-02-01
• First posted: 2005-09-16
• Last updated: 2025-02-06

Locations

1 site across 1 country: United States