Clinical Trials Directory

Trials / Terminated

TerminatedNCT00179751

A Phase I/II Study of Lenalidomide in Combination With Gemcitabine in Patients With Untreated Advanced Carcinoma of the Pancreas

A Phase I/II Study Of Lenalidomide (Revlimid ) In Combination With Gemcitabine In Patients With Untreated Advanced Carcinoma Of The Pancreas

Status
Terminated
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
50 (planned)
Sponsor
Celgene Corporation · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Phase I will determine the MDT and evaluate the safety profile of oral lenalidomide days 1-21 and weekly gemcitabine days 1, 8, \& 15 in 28 day cycles Phase II will explore the anti-tumor activity and safety of the combination in subjects with advanced pancreatic carcinoma. Subjects will receive oral lenalidomide days 1-21 and weekly gemcitabine days 1, 8, \& 15 in 28 day cycles until documented disease progression occurs.

Conditions

Interventions

TypeNameDescription
DRUGCC-5013
DRUGgemcitabine

Timeline

Start date
2005-04-01
Completion
2006-08-01
First posted
2005-09-16
Last updated
2005-11-07

Locations

6 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00179751. Inclusion in this directory is not an endorsement.