Trials / Terminated
TerminatedNCT00177060
Topical Hydromorphone for Wound Healing
- Status
- Terminated
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- Hordinsky, Maria K., MD · Individual
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
The hypothesis is that topical opioids will hasten wound healing in humans.
Detailed description
This is based on our published data that morphine is a powerful stimulant of angiogenesis and our preclinical study of wounds in rats which demonstrate that topical opioids (morphine, hydromorphone and fentanyl) hasten healing of punch biopsy wounds. This study will focus on hydromorphone which was more powerful than morphine as a wound-healer in the rat study.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | hydromorphone |
Timeline
- Start date
- 2003-10-01
- Completion
- 2007-05-01
- First posted
- 2005-09-15
- Last updated
- 2010-03-01
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00177060. Inclusion in this directory is not an endorsement.