NCT00175149

Active Vitamin D Effect on Left Ventricular Hypertrophy

The Efficacy of 1,25 Dihydroxycholecalciferol on the Cardiovascular System in Patients With Renal Dysfunction

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Per Ivarsen · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Left ventricular hypertrophy (LVH) predicts mortality at start of dialysis. Prevention of of LVH is important. It is not known whether secondary hyperparathyroidism might induce LVH. In the present study patients are randomised to 1.25 dihydroxycholecalciferol or no treatment to study the effect on LVH.

Conditions

• Chronic Kidney Disease
• Secondary Hyperparathyroidism
• Left Ventricular Hypertrophy

Interventions

Type	Name	Description
DRUG	Alfacalcidiol	Alfacalcidiol are given to patientwith CKD 3-4 and secondary hyperparathyrodism. The PTH level is lowered to normal range. with increasing dose of alfacalcidiol and are followed for 6 month.

Timeline

• Start date: 2002-01-01
• Primary completion: 2008-12-01
• Completion: 2008-12-01
• First posted: 2005-09-15
• Last updated: 2015-12-08

Locations

1 site across 1 country: Denmark