Clinical Trials Directory

Trials / Completed

CompletedNCT00171730

An Extension Study to Assess the Long-Term Safety and Efficacy of Pasireotide in Participants With Acromegaly

Extension to a Multi-Center, Randomized, Crossover, Open Label, Dose Finding Study to Compare the Safety, Efficacy, and Pharmacokinetics/Pharmacodynamics (PK/PD) Relationship of Multiple Doses of Pasireotide (SOM230) (200, 400, and 600 μg Bid) and Doses of Open Label Sandostatin® (SMS) (100 μg Tid) in Acromegalic Patients

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
30 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Acromegaly is a rare, serious condition characterized by chronic hypersecretion of growth hormone (GH), generally caused by a GH-secreting pituitary adenoma. The study assessed the long-term safety and efficacy of pasireotide in participants with acromegaly.

Conditions

Interventions

TypeNameDescription
DRUGPasireotide

Timeline

Start date
2004-08-24
Primary completion
2013-12-06
Completion
2013-12-06
First posted
2005-09-15
Last updated
2021-09-05
Results posted
2021-06-02

Locations

10 sites across 7 countries: United States, Australia, Belgium, France, Germany, Italy, Switzerland

Regulatory

Source: ClinicalTrials.gov record NCT00171730. Inclusion in this directory is not an endorsement.