Trials / Completed
CompletedNCT00170222
Placebo Versus Antibiotics in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
The Value of Antibiotic Treatment of Exacerbations of Hospitalised COPD Patients
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 258 (estimated)
- Sponsor
- Medical Center Alkmaar · Academic / Other
- Sex
- All
- Age
- 45 Years
- Healthy volunteers
- Not accepted
Summary
The role of antibiotic therapy in patients with COPD remains controversial. While the outcome of several clinical trials is in favour of antibiotics, the quality of these studies in insufficient. In this study the efficacy of doxycycline is compared to placebo. All concommitant treatment (steroids, bronchodilator therapy, physiotherapy) is standardized. The investigators hypothesize that patients with an acute exacerbations will have a better outcome when treated with antibiotics.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | doxycycline |
Timeline
- Start date
- 2002-07-01
- Primary completion
- 2008-08-01
- Completion
- 2008-08-01
- First posted
- 2005-09-15
- Last updated
- 2008-09-29
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT00170222. Inclusion in this directory is not an endorsement.