Trials / Completed
CompletedNCT00169065
Effectiveness of Clozapine Versus Olanzapine for Treatment-resistant Schizophrenia
Clozapine vs. Olanzapine: An Effectiveness Study
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 38 (actual)
- Sponsor
- Harvard Medical School (HMS and HSDM) · Academic / Other
- Sex
- All
- Age
- 20 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
This study will determine the effectiveness of clozapine versus olanzapine in treating people with schizophrenia that has not improved with treatment.
Detailed description
This is a two-year open-label, randomized trial of the comparative effectiveness of clozapine versus olanzapine in patients with treatment refractory schizophrenia. The objective is to determine whether in a naturalistic setting olanzapine is a logical treatment choice (before using the more toxic clozapine) for some treatment refractory patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Clozapine | |
| DRUG | Olanzapine |
Timeline
- Start date
- 1998-08-01
- Primary completion
- 2002-06-01
- Completion
- 2002-06-01
- First posted
- 2005-09-15
- Last updated
- 2015-04-07
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00169065. Inclusion in this directory is not an endorsement.