NCT00167414

Study for Using Radiosurgery on Limited Metastases of Breast Cancer

A Phase II Study for Using Radiosurgery on Limited Metastases of Breast Cancer

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 49 (actual)
• Sponsor: University of Rochester · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate whether radiosurgery, along with standard chemotherapy, immunotherapy (the treatment of cancer by modulating the immune system and immune response), or hormonal therapy, affects the quality and length of life. The standard therapy is surgery, radiation therapy, or chemotherapy alone or in any combination. A second purpose of this study is to determine if the levels of a special type of protein (called cytokines) found in the blood are related to the quality of life while on this treatment.

Detailed description

Before treatment begins, you will have a physical exam and blood tests. Physical evaluations and blood tests will be done each week while you are receiving treatment, and at follow-up visits. You will be seen for follow-up evaluations 4 weeks after treatment is completed, and every three months thereafter. You will be asked to fill out a Quality of Life questionnaire, which should take 5-10 minutes to complete. This will be done prior to treatment and at your follow-up visits. You will receive high dose radiation therapy directed at the site of metastasis. This treatment will be given once a day, 5 times a week (Monday through Friday) for one to four weeks depending on the location and size of the disease to be treated.

Conditions

• Breast Cancer, Metastatic

Interventions

Type	Name	Description
PROCEDURE	Hypofractionated Stereotactic Body Radiation Therapy	Hypofractionated Stereotactic Body Radiation Therapy
RADIATION	Hypofractionated Stereotactic Body Radiation Therapy	Hypofractionated Stereotactic Body Radiation Therapy for treatment of limited metastases from breast cancer primary.

Timeline

• Start date: 2000-12-01
• Primary completion: 2016-11-01
• Completion: 2016-11-01
• First posted: 2005-09-14
• Last updated: 2018-01-05
• Results posted: 2018-01-05

Locations

1 site across 1 country: United States