NCT00165412

Breast MRI Screening in Women Treated With Mediastinal Irradiation for Hodgkin's Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 148 (actual)
• Sponsor: Dana-Farber Cancer Institute · Academic / Other
• Sex: Female
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine if the use of breast MRI in detecting breast malignancies in survivors of Hodgkin's disease is more successful than the traditional mammogram.

Detailed description

* The screening breast MRI and mammography will be performed 6 months or longer after the last mammogram. For pre-menopausal women, the screening will be performed during the second week of the menstrual cycle to reduce cycle-related breast changes. As much as possible, the breast MRI and mammogram are to be performed on the same day. * On the day of the breast imaging studies, the patient will also be asked to fill out a baseline breast health questionnaire, which includes questions on time since radiation therapy, prior screening history, history of prior benign breast biopsies, menopausal status, prior hormonal therapy use, etc. * In patients with suspicious findings or findings highly suggestive of malignancy, the abnormal findings will be reviewed with the patient and recommendations will be made for a biopsy.

Conditions

• Breast Cancer
• Hodgkin's Disease

Interventions

Type	Name	Description
PROCEDURE	breast MRI	Repeated once a year for three years
PROCEDURE	Mammogram	Repeated once a year for three years

Timeline

• Start date: 2005-07-01
• Primary completion: 2010-05-01
• Completion: 2010-05-01
• First posted: 2005-09-14
• Last updated: 2019-05-02

Locations

3 sites across 1 country: United States