Trials / Terminated
TerminatedNCT00164801
Effect of GABAB Agonist on Visceral Hyperalgesia in NCCP patientsChinese?
Is Visceral Hyperalgesia the Culprit of Noncardiac Chest Pain in Chinese? Part 2: Effect of GABAB Agonist on Visceral Hyperalgesia in NCCP Patients
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- Chinese University of Hong Kong · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- —
Summary
The effect of baclofen (GABAB agonist), diltiazem (muscle relaxant) and placebo will be compared in a double-blinded randomized study for the treatment of NCCP. Cerebral cortical, brainstem and spinal evoked potentials before and after treatment will be evaluated. Results of this study will shed lights on pathogenesis and treatment of NCCP in Chinese.We hypothesize that Baclofen alleviates visceral hyperalgesia in NCCP patients by suppressing afferent sensory pathway.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Baclofen, Diltiazem |
Timeline
- Start date
- 2004-11-01
- Completion
- 2007-01-01
- First posted
- 2005-09-14
- Last updated
- 2008-03-26
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT00164801. Inclusion in this directory is not an endorsement.