NCT00162617

The Effect of Liberal vs. Restrictive Transfusion Strategies on Rehabilitation After Hip Fracture Surgery

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 120 (planned)
• Sponsor: Hvidovre University Hospital · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

To examine the effect of two different transfusion regimens on rehabilitation after hip fracture surgery.

Detailed description

The effect of liberal vs restrictive transfusion regimens after hip fracture surgery is unresolved. Liberal transfusion regimens (transfusion trigger hgb. 6.25 mmol/l) leads to an increased use of blood products but may impact positively on rehabilitation outcome, a restrictive transfusion trigger (hbg. 5.0 mmol/l) saves blood products but may also impair postoperative rehabilitation and outcome. the study randomizes 120 elderly patients with hip fractures to either a restrictive or a liberal perioperative transfusion therapy and measures postoperative rehabilitation outcomes within a well defined multimodal rehabilitation regimen.

Conditions

• Hip Fracture

Interventions

Type	Name	Description
DRUG	Red blood cell transfusion

Timeline

• Start date: 2004-01-01
• Completion: 2006-03-01
• First posted: 2005-09-13
• Last updated: 2011-08-30

Locations

1 site across 1 country: Denmark