NCT00160719

HLA Sensitization Following Major Cortical Allograft Bone Procedures

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 10 (actual)
• Sponsor: University of Florida · Academic / Other
• Sex: All
• Age: 12 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to find out whether or not antibodies to the donor bone are present in the blood of patients who receive the donor bone.

Detailed description

Patients who have bone cancer often have the cancerous bone removed by surgery and replaced with a piece of bone taken from a donor (a person who donates parts of their body to be used for transplants after their death). However, sometimes this replacement bone does not heal together with the patient's bone. The reason the bone does not heal is not known but it is thought that the patient's body may react to the donor bone by producing antibodies against cells on the donor bone. The purpose of this study is to find out whether or not antibodies to the donor bone are present in the blood of patients who receive the donor bone. You have been asked to participate in this study because you are scheduled to undergo this type of surgery.

Conditions

• Bone Cancer

Interventions

Type	Name	Description
PROCEDURE	retrieve blood samples	blood samples obtain pre-op, 6 and 12 months post-op

Timeline

• Start date: 1999-09-01
• Primary completion: 2010-03-01
• Completion: 2010-03-01
• First posted: 2005-09-12
• Last updated: 2012-10-30

Locations

1 site across 1 country: United States