Clinical Trials Directory

Trials / Completed

CompletedNCT00159120

Maintenance Treatment vs. Stepwise Drug Discontinuation in First-Episode Schizophrenia

Maintenance Treatment vs. Stepwise Drug Discontinuation After One Year of Maintenance Treatment in First-Episode Schizophrenia

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
71 (estimated)
Sponsor
Heinrich-Heine University, Duesseldorf · Academic / Other
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Not accepted

Summary

After one year neuroleptic maintenance treatment in patients with first episode schizophrenia, neuroleptic treatment will be continued vs. stepwise discontinued (randomized design) over a period of 1 year. Under both conditions prodrome based early intervention take place.

Detailed description

After one year neuroleptic maintenance treatment in patients with first episode schizophrenia, neuroleptic treatment will be continued vs. stepwise discontinued (randomized design) over a period of 1 year. Under both conditions pharmacologic early intervention strategies in case of early sign of relapse will be applied.

Conditions

Interventions

TypeNameDescription
OTHERmaintained antipsychotic treatment vs. stepwise drug discontinuationmaintained antipsychotic treatment (in low dose) vs. stepwise drug discontinuation; both supplemented by prodrome-based early intervention; 1 year

Timeline

Start date
2001-11-01
Primary completion
2006-06-01
Completion
2006-06-01
First posted
2005-09-12
Last updated
2008-01-30

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT00159120. Inclusion in this directory is not an endorsement.