Trials / Completed
CompletedNCT00154050
High Dose Candesartan Versus Quinapril for Restenosis Prophylaxis After Stent Angioplasty
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 22 (planned)
- Sponsor
- Technische Universität Dresden · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The study is designed to test the hypothesis that high dose candesartan treatment compared to quinapril is able to reduce intima hyperproliferation and the restenosis rate after stent angioplasty in peripheral occlusive artery disease.
Detailed description
Patients are randomly assigned to treatment with either candesartan 32 mg/d or Quinapril 20 mg/d before the angioplasty. Walking distance, intima media thickness and crurobrachial pressure ratios are compared after 6 weeks, 3 months and 6 months. After 6 months an angiographic control is performed.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | candesartan (drug) or quinapril (drug) |
Timeline
- Start date
- 2004-05-01
- Completion
- 2006-07-01
- First posted
- 2005-09-12
- Last updated
- 2006-09-12
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00154050. Inclusion in this directory is not an endorsement.