NCT00153699

Relationship Between Topiramate Use and Ocular Angle Status

Relationship Between Topiramate Use and Ocular Angle Status: A Prospective Pilot Study

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 15 (estimated)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

We test the hypothesis whether topiramate narrows the angles which may render Asians more likely to suffer from acute angle closure glaucoma.

Detailed description

Topiramate is approved for the treatment of epilepsy and prophylaxis of migraine attacks. There were case reports of acute angle closure glaucoma (AACG) associated with its use. AACG is particularly common in Asians because of a higher prevalence of narrow angle., we test the hypothesis whether topiramate narrows the angles which may render them more likely to suffer from AACG.

Conditions

• Glaucoma, Angle-Closure

Interventions

Type	Name	Description
DRUG	Topiramate

Timeline

• Start date: 2004-09-01
• Completion: 2007-07-01
• First posted: 2005-09-12
• Last updated: 2007-10-31

Locations

2 sites across 1 country: Hong Kong