NCT00152724

Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers

Etude de la Reserve Vasomotrice Microcirculatoire cutanée

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 85 (actual)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Microvascular dysfunctions are critical events in several diseases including diabetes. This study will develop a methodology for microvascular investigation in human skin. The purpose of the study is to investigate the physiological response of the cutaneous microcirculation to physical, thermal, mechanical or chemical stimulations.

Detailed description

This study has investigated various aspects of the physiology of the microcirculation in the past years and is still recruiting under parallel protocols of physiological investigations of the neurovascular control of the cutaneous microcirculation.

Conditions

• Healthy Volunteers

Interventions

Type	Name	Description
DEVICE	pressure strain system, iontophoresis
DRUG	scopolamin
DRUG	emla
DRUG	capsaicin
DRUG	aspirin
DRUG	clopidogrel
DRUG	celecoxib
DRUG	indomethacin
DRUG	acetylcholine
DRUG	sodium nitroprusside
DRUG	brethyllium
DEVICE	general and local heating

Timeline

• Start date: 1996-01-01
• Primary completion: 2008-11-01
• Completion: 2008-11-01
• First posted: 2005-09-09
• Last updated: 2017-11-01

Locations

1 site across 1 country: France