NCT00151827

Olmesartan Medoxomil in Hypertension and Renal Impairment

Efficacy and Safety of Olmesartan Medoxomil Compared With Losartan in Patients With Hypertension and Mild to Moderate Renal Impairment

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 393 (actual)
• Sponsor: Sankyo Pharma Gmbh · Industry
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This is a study in hypertensive patients with mild to moderate renal impairment. The antihypertensive efficacy of olmesartan medoxomil is compared to losartan.

Conditions

• Essential Hypertension
• Renal Impairment

Interventions

Type	Name	Description
DRUG	Olmesartan medoxomil	Olmesartan oral tablets 20 or 40 mg + losartan placebo. Medications are taken once daily before breakfast with water.
DRUG	Losartan	Medications are taken once daily before breakfast with water.
DRUG	Furosemide oral tablets	If its use is necessary, the dose of furosemide allowed is 20 to 120 mg per day at the discretion of the investigator

Timeline

• Start date: 2003-08-01
• Primary completion: 2005-07-01
• Completion: 2005-07-01
• First posted: 2005-09-09
• Last updated: 2010-10-14

Locations

1 site across 1 country: Germany