Trials / Completed
CompletedNCT00151008
Bexarotene With Narrow-Band UVB for Psoriasis
Investigator-Initiated, Double Blind, Vehicle-Controlled, Bilateral Comparison Trial of Bexarotene (Targretin) Gel 1% vs. Vehicle Gel in Combination With Narrow Band UVB Phototherapy for Moderate to Severe Psoriasis Vulgaris
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 35 (planned)
- Sponsor
- University of Medicine and Dentistry of New Jersey · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To determine if bexarotene gel with NBUVB phototherapy is more effective than placebo plus NBUVB for moderate to severe plaque-type psoriasis.
Detailed description
Subjects will be applying active gel or placebo to target lesions to each side of the body in a blinded manner. They will start at three times a week and increase to daily or even twice a day regimen if tolerated. After 2 weeks of application, NBUVB will be added to treatment regimen (whole body, three times a week). Total study time is 10 weeks.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Bexarotene/NBUVB vs placebo NBUVB |
Timeline
- Start date
- 2003-11-01
- Completion
- 2005-08-01
- First posted
- 2005-09-08
- Last updated
- 2008-08-07
Source: ClinicalTrials.gov record NCT00151008. Inclusion in this directory is not an endorsement.